MRI-based diagnostic and therapeutic strategies, by integrating nanotechnology with imaging, offer new avenues for the precision treatment of lymphoma.However, their clinical application remains limited due to challenges in targeting efficiency and safety concerns.Future advancements will require innovations in materials science and interdisciplinary collaboration to facilitate the translational development of theranostic nanomedicines from bench to bedside.

With changes in lifestyle and an increasingly fast-paced way of living, obesity has become a global public health issue.In China, the prevalence of obesity continues to rise, drawing significant attention from the National Health Commission.On October 17, 2024, the National Health Commission officially released the Clinical Guidelines for the Diagnosis and Treatment of Obesity (2024 Edition) — the first multidisciplinary clinical guidelines for obesity in the country.

This study proposes a novel platform that integrates low-field nuclear magnetic resonance (NMR) technology with process analytical technology (PAT).The results demonstrate that this combined approach can not only be applied to the study of drying kinetics in materials such as food, medicinal herbs, and wood, but also serve as an experimental platform or tool for the design and manufacturing of processing equipment used in the preparation of traditional Chinese medicine (TCM) decoction pieces.

Low-field nuclear magnetic resonance (LF-NMR) time-domain technology and low-field magnetic resonance imaging (LF-MRI) were employed to perform both qualitative and quantitative analysis of the wetting agent (ethanol) during high-shear granulation.

Low-field nuclear magnetic resonance (NMR) technology has been applied for many years in the fields of materials science, chemical engineering, and the food industry.Its fundamental principle is based on detecting nuclear magnetic signals from hydrogen protons within the sample. This allows for qualitative analysis by distinguishing different hydrogen environments, or quantitative analysis by utilizing the linear relationship between signal intensity and the number of hydrogen protons present in the sample.For example, GB/T 6504-2008 Test Method for Oil Content in Chemical Fibers, and GB/T 31743-2015 Determination of Solid Fat Content in Animal and Vegetable Fats and Oils by Pulsed NMR — Direct Method.

As a green and non-destructive analytical method, low-field nuclear magnetic resonance (NMR) technology can effectively support research on food and medicinal substances in both the food industry and traditional Chinese medicine fields.Built on its cross-disciplinary applicability, it also helps clients develop a wider range of innovative solutions.

Low-field nuclear magnetic resonance (NMR) technology is highly sensitive to water molecules with varying degrees of mobility within pharmaceutical materials. By using water as a "probe," low-field NMR can analyze relaxation information to characterize the microscopic changes in water during the drug soaking process. This enables real-time monitoring of the soaking behavior of pharmaceutical substances through low-field NMR.

Encapsulation efficiency is a critical quality attribute of liposomes.It refers to the percentage of the drug encapsulated within the lipid bilayer relative to the total amount of drug added.This parameter reflects the extent to which the drug is successfully incorporated into the liposomes and serves as an important indicator for optimizing the formulation and preparation process.

Water dispersible granules (WDGs) are a type of granular formulation that rapidly disintegrates and disperses into a suspension upon contact with water.They were formerly referred to in the United States as dry flowables or dry suspensions.

Polymorphism is a widespread phenomenon in solid compounds, and the polymorphic forms of drugs can significantly affect the quality and therapeutic efficacy of solid pharmaceutical products.As a result, research in this area has attracted increasing attention from scientists both in China and abroad.