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Содержание фтора во фторидной зубной пасте проверено методом низкопольного ЯМР

Содержание фтора во фторидной зубной пасте проверено методом низкопольного ЯМР

Fluoride Toothpaste

Fluoride toothpaste refers to toothpaste that contains fluoride. Scientists have found that fluoride can effectively prevent dental caries and enhance the ability of teeth to resist caries. For children, especially children under 6 years old, due to poor swallowing reflex, attention should be paid to prevent excessive fluoride intake.

Fluorine Content Effects Fluoride Toothpaste

1. Directly inhibit the bacteria of dental plaque: Fluorine has an inhibitory effect on acid-producing bacteria. It can inhibit the storage of intracellular polysaccharide of Streptococcus cariogenicum, affecting the growth and reproduction of bacteria; inhibit the synthesis of extracellular polysaccharide by Streptococcus cariogenicum, and reduce the adhesion of bacteria and plaque on the tooth surface.

2. The effect of fluoride on tooth enamel: The dental pellicle is the basis for bacteria to attach to the tooth surface, and fluorine plays an important role in inhibiting the formation of dental pellicle and the growth of plaque. The exchange of fluoride ions with hydroxide ions in enamel hydroxyapatite to form fluorapatite will enhance the structure of enamel, reduce solubility, and enhance anti-caries ability.

3. Promotes mineralization: Promotes remineralization of enamel that has been demineralized at the beginning of caries.

Fluorine Content Tested by Niumag NMR

Fluorine content can be measured quickly and accurately using low-field NMR, independent of fluoride compounds and toothpaste formulations. The method is fast, easy to operate and calibrate, and requires no additional sample preparation and can be used without training. The speed and simplicity of NMR makes it the leading method for fluorine content testing in manufacturing, product development and quality control.

Fluorine Content Measurement by NMR

Метод ЯМР основан на линейной зависимости между содержанием ядер фтора в образце и интенсивностью сигнала ЯМР.. Амплитуда сигнала ЯМР пропорциональна массе растворимого фтора., и через эту линейную зависимость, содержание фтора в тестируемом образце можно быстро определить.

Since solid or insoluble fluorine signals decay very quickly, such as in calcium fluoride (CaF2) or magnesium fluoride (MgF2), only soluble fluorine is detected in the NMR signal. Измерение проводилось с использованием последовательности спинового эха.. Фигура 1 shows the spin echo sequence and the detected NMR signal. Распад свободной индукции (ПИД) Сигнал ЯМР измерялся в момент времени 1 после 90-градусного радиочастотного импульса.. At this point the signal intensity (А1) is the sum of the soluble and insoluble fluorine signals in the sample. После 180-градусного импульса, амплитуда обнаруженного сигнала спин-эха равна A2. В это время, the signal of insoluble fluorine has been attenuated to 0, and A2 is only the signal intensity of soluble fluorine. Поэтому, the signal intensity A2 is proportional to the fluorine content of the sample.

Niumag NMR Analyzer for Fluoride Content Test

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